Wear appropriate protective eyeglasses or chemical safety goggles as described by oshas eye and face protection regulations in 29 cfr 1910. It is a benzoate ester and a member of salicylates. Burning cold, heat these sensations can all work together so that when we apply methyl salicylate containing creams, lotions, or ointments we feel a warming sensation. It is used as a perfumery like magnolia, meadowsweet, root beer. Do not give methyl salicylate and menthol cream and ointment to a child younger than 12 years old without first checking with the doctor. It is a clear liquid that is sparingly soluble in water, but soluble in alcohol and ether. Methyl salicylate is an organic compound present mainly in wintergreen oil obtained from gaultheria procumbens. Nov 09, 2018 methyl salicylate topical for the skin is used for temporary relief of muscle or joint pain caused by strains, sprains, arthritis, bruising, or backaches. Methyl salicylate definition of methyl salicylate by. Chemical properties of methyl salicylate alisahonghong.
Methyl salicylate topical for the skin is used for temporary relief of muscle or joint pain caused by strains, sprains, arthritis, bruising, or backaches. Pubchem is the worlds largest collection of freely accessible chemical information. In methyl salicylate oil of wintergreen, the cooh group of salicylic acid is esterified with methanol ch 3 oh, whereas in acetylsalicylic acid aspirin the acid component of the ester is acetic acid, and salicylic acid contributes the phenolic. Analysis of the spectrum supports the above assignments.
Methyl salicylate oil of wintergreen or wintergreen oil is an organic compound with the formula c 6 h 4 ohco 2 ch 3. It is produced by many species of plants, particularly wintergreens. Methyl salicylate and the volatile methyl acetate are formed at the same time, the latter being removed by evaporation when reaction crude is processed. The nontoxic nature compared to xylene and rapid clearing property of methyl salicylate encouraged us to include it in our study. Methyl salicylate is used in flavoring for foods, candies, beverages and pharmaceuticals. Methyl salicylate, the methyl ester of salicylic acid. Methyl salicylate is commonly used as spices of food, toothpaste and cosmetics. Chemical ecology and phytochemistry of forest ecosystems. The aim of this study is to shorten the turnaround time and use of alternate nontoxic chemical in tissue processing which is also costeffective. To apply a methyl salicylate topical skin patch, remove the liner and apply the patch to your skin over the area of pain.
Synthesis of oil of wintergreen pre lab discussion. Wintergreen the good, the bad, the ugly naturopathic doctor. Methyl salicylate oil of wintergreen or wintergreen oil is an organic ester naturally produced by many species of. Methyl salicylate may be used by plants as a pheromone to warn other plants of. Nov 02, 2017 the nontoxic nature compared to xylene and rapid clearing property of methyl salicylate encouraged us to include it in our study.
Sigmaaldrich offers a number of methyl salicylate products. Methyl salicylate, nf is used to treat minor aches and pains of the muscles and joints. Methyl salicylate is an external analgesic available in overthecounter otc medicines that temporarily relieve minor body aches and muscle and joint pain associated with backache, arthritis, strains, sprains, and bruises. It has counter irritant and antiinflammatory effects. Methyl salicylate, nf 119368 me170 spectrum chemical. Salicylate is a monohydroxybenzoate that is the conjugate base of salicylic acid. Find chemical and physical properties, biological activities, safety and toxicity information, patents, literature citations and more. Synthesis of oil of wintergreen cornell center for. Methyl salicylate is a topical analgesic, as is capsaicin and menthol. Methyl salicylate definition of methyl salicylate by the. Chemical properties methyl salicylate has a characteristic wintergreenlike odor.
Heat is also generated by the interaction of esters with caustic solutions. Salicylates, including salicylic acid sa, methyl salicylate, saligenin and their respective glucosides, are natural products of plant metabolism that have long been known to possess therapeutic properties. Methyl salicylate,119368,price,manufacturer,supplier. Search chemicals by name, molecular formula, structure, and other identifiers.
Find patient medical information for methyl salicylatementhol topical on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Methyl salicylate c8h8o3 structure, molecular mass, properties. Methyl salicylate 119368 chemicalbookchemical search. Methyl salicylate oil of wintergreen is prepared by heating salicylic acid, c 7 h 6 o 3, with methanol, ch 3 oh. It has a role as a flavouring agent, a metabolite and an insect attractant. Visit chemicalbook to find more methyl salicylate119368 information like chemical properties,structure,melting point,boiling point,density,molecular formula. It is also synthetically produced, used as a fragrance, in foods and beverages, and in liniments. It is a colorless liquid with a sweet, phenolic odor. If an internal link led you here, you may wish to change the link to point directly to the intended article.
It is a colorless, viscous liquid with a sweet fruity odor reminiscent of root beer. Methyl salicylate c8h8o3 cid 43 structure, chemical names, physical and chemical properties. Bakers best arthritis pain relief cream arthritis cream, pain relief, topical numbing cream methyl salicylate, menthol, lidocaine, aloe vera gel, emu oil, glucosamine sulfate, msm 2 oz 4. Methyl salicylate is found in trees, legumes and exotic plants. Methyl salicylate oil of wintergreen is prepared by. It is also found in the essential oils of cassie absolute, betula, tea tree and all plant species belonging to the genera spiraea, polygala, etc. It is also known by other names such as wintergreen oil, betula oil, sweet birch oil, gaultheria oil, tea berry oil and so on. Oct 04, 2019 to apply a methyl salicylate topical skin patch, remove the liner and apply the patch to your skin over the area of pain. This set index page lists chemical compounds articles associated with the same name. In addition to the thermodynamics research center trc data available from this site, much more physical and chemical property data is available from the following trc products. Methyl salicylate or methyl 2hydroxybenzoate, also known as wintergreen oil, is a natural product and is present in white wine, tea, porcini mushroom boletus edulis, bourbon vanilla, clary sage, red sage and fruits including cherry, apple, raspberry, papaya and plum. Methyl salicylate chemicalbookchemical search engine. Spectrum chemical nf products are manufactured, packaged and stored under current good manufacturing practices cgmp per 21cfr part 211 in fda registered and inspected facilities. Stars, this entity has been manually annotated by the chebi team.
It is also used to produce antalgesic drugs, pesticides, rubbing agent, ink, etc. Find patient medical information for methyl salicylate on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. The methyl ester of salicylic acid, c8h8o3, an essential oil derived from birch or wintergreen or made synthetically, used as a counterirritant in ointments to treat muscle pain. The c dept 5 nmr experiment shows all tertiary r 3ch and primary rch3 carbons up and secondary r2ch2 carbons down. This structure is also available as a 2d mol file or as a computed 3d sd file. Visit byjus to understand the properties, structure. Methyl salicylate can be used for food flavor formula, is a food flavor within chinas gb27601996 provisions of the temporary use, adi value of 0 to 0. Methyl salicylate price,buy methyl salicylate chemicalbook. Methyl salicylate an overview sciencedirect topics. Feb 04, 2020 if methyl salicylate and menthol cream and ointment is swallowed, call a doctor or poison control center right away. The medical examiner determined that an abnormally elevated level of methyl salicylate in her body was the cause of death. This structure is also available as a 2d mol file or as a computed 3d sd file the 3d structure may be viewed using java or javascript.
Methyl salicylate, the methyl ester of salicylic acid index of chemical compounds with the same name this set index page lists chemical compounds articles associated with the same name. Methyl salicylate is the main constituent of oil of wintergreen and is used in linaments, etc. The odor is often described as minty due to its use in mint candies. Remove the patch and apply a new patch 1 or 2 times daily if needed. It has a pleasant odor resembling wintergreen and is used in perfumery and artificial flavors. If you are 60 or older, use methyl salicylate and menthol cream and ointment with care. Methyl salicylate, c 8 h 8 o 3 chemical formula c 6 h 4 hocooch 3 other names. Srd 103a thermo data engine tde for pure compounds. Potassium salicylate is the potassium salt of salicylic acid.
Nov 19, 2016 it is an ester of menthol and salicylic acid with the chemical formula c 8 h 8 o 3. Numbing might follow depending on the concentration of methyl salicylate is applied. Again, the hydroxy group is ortho and paraactivating so the carbon signals at c2, c4 and c6 should experience upfield shifts. Methyl salicylate c6h4 ho cooch3, also known as salicylic acid methyl ester, oil of wintergreen, is a natural product of many species of plants. Chemical properties methyl salicylate is the main component of wintergreen oil and occurs in small quantities in other essential oils and fruits. Methyl salicylate topical may be used up to 4 times daily or as directed on the medicine label. The fcc grade meets the requirements of the food chemical codex indicates and is suitable for all food, beverage and nutritional supplement applications. Methyl salicylate, fcc is used as a fragrant in food and beverages. Methyl salicylate appears as a colorless to yellowish or reddish liquid, which is clear and viscous in. Methyl salicylate is an antiinflammatory ingredient common in pain relief creams for muscles and joints. Srd 103b thermo data engine tde for pure compounds, binary mixtures and chemical reactions.
Safety data sheet according to 29cfr19101200 and ghs rev. Receptor neurons detecting the typical plant stress compound methyl salicylate have been identified in the moth m. Application methyl salicylate has been used in the hyalinization of tissues for pulmonary angiography. Methyl salicylate functions as a flavouring agent in chewing gums, syrups and ice creams. Structure, properties, spectra, suppliers and links for. Interestingly, methyl salicylate and methyl benzoate are both produced by methylation of salicylic and benzoic acids, respectively, controlled by the same gene in a. Ethyl salicylate is the ester formed by the condensation of salicylic acid and ethanol. Methyl salicylate c8h8o3 methyl salicylate is an ester of salicylic acid with chemical formula c8h8o3. Esters react with acids to liberate heat along with alcohols and acids. Refractive index of c8h8o3 methyl salicylate rheims.
Methyl salicylate oil of wintergreen or wintergreen oil is an organic ester naturally produced by many species of plants, particularly wintergreens. Methyl salicylate nutzen, nebenwirkungen, bewertungen. Wear appropriate protective eyeglasses or chemical safety goggles as described by oshas eye and face protection regulations in. Methyl salicylate oil of wintergreen or wintergreen oil is an organic compound. Methyl salicylate is a benzoate ester that is the methyl ester of salicylic acid. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Methyl salicylate oil of wintergreen is prepared by heating. Brand names of formulations containing methyl salicylate are balmosa, monphytol, phytex, radian b and salonpas.
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